Author's response to reviews Title: Temperature Influence on DXA measurements: Bone Mineral Density acquisition in frozen and thawed human Femora Authors:
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Temperature influence on DXA measurements: bone mineral density acquisition in frozen and thawed human femora
BACKGROUND Determining bone mineral density (BMD) with dual-energy x-ray absorptiometry (DXA) is an established and widely used method that is also applied prior to biomechanical testing. However, DXA is affected by a number of factors. In order to delay decompositional processes, human specimens for biomechanical studies are usually stored at about -20 degrees C; similarly, bone mineral densit...
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pQCT provides better prediction of canine femur breaking load than does DXA.
Our study was designed to examine the validity of dual energy X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT) measurements as predictors of whole bone breaking strength in beagle femora. DXA was used to determine the bone mineral content, bone area, and 'areal' bone mineral density. PQCT was used to determine the cross-sectional moments of inertia, volumetric d...
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